Platelet Activating Factor

A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.

Also Known As:

1- Alkyl- 2- acetyl- sn- glycerophosphocholine; Platelet Aggregating Factor; Platelet Aggregation Enhancing Factor; Platelet-Activating Substance; Thrombocyte Aggregating Activity; 1 Alkyl 2 acetyl sn glycerophosphocholine; Aggregating Factor, Platelet; Factor, Platelet Activating; PAF Acether; Platelet Activating Substance; AGEPC; Acetyl Glyceryl Ether Phosphorylcholine; PAF-Acether; Phosphorylcholine, Acetyl Glyceryl Ether

Organic Chemicals: 133
- Amines: 4871
  - Quaternary Ammonium Compounds: 136
    - Trimethyl Ammonium Compounds: 1
      - Choline: 6256
        Platelet Activating Factor: 2984
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - Choline: 6256
        Platelet Activating Factor: 2984
- Alcohols: 595
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - Choline: 6256
        Platelet Activating Factor: 2984
- Onium Compounds
  - Quaternary Ammonium Compounds: 136
    - Choline: 6256
      - Platelet Activating Factor: 2984
Lipids: 114793
- Membrane Lipids: 1591
  - Phospholipids: 11903
    - Glycerophosphates: 118
      - Phosphatidic Acids: 358
        Glycerophospholipids: 689
        Phospholipid Ethers: 36
        Platelet Activating Factor: 2984
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Platelet Activating Factor: 2984
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Platelet Activating Factor: 2984

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Disease

Drug/Important Bio-Agent (IBA)